No association of leukemia inhibitory factor (LIF) DNA polymorphisms with multiple sclerosis
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چکیده
منابع مشابه
Investigation of Leptin, Leukemia Inhibitory Factor (LIF), and IL-6 Serum Levels in Myeloid Leukemia
Background: Leptin has been implicated in the differentiation and proliferation of hematopoietic cells. Leukemia inhibitory factor (LIF) may play an important role, along with Interleukin-6 (IL-6) and granulocyte colony stimulating factor (G- CSF), in the regulation of early hematopoietic stem cells. The aim of the study was to evaluate serum level of leptin, LIF, and IL-6 in myeloid leukemia p...
متن کاملLeukemia inhibitory factor (LIF) and LIF receptor in human lung. Distribution and regulation of LIF release.
The distribution and regulation of leukemia inhibitory factor (LIF) and its receptor (LIFR) in human lung tissue is unknown. We recently found that LIF was immunolocalized to several cell types in human airways, and that exogenous LIF modulated neural and contractile responses of explanted airways. The present study aimed to determine the cellular distribution and regulation of gene transcripts...
متن کاملThe Comparison of Leukemia Inhibitory Factor (LIF) Concentration in the Serum and Cerebrospinal Fluid of Children with Bacterial Meningitis
Abstract Background and objectives: Meningitis is one of the most common infectious of the central nervous system (CNS), defined as an inflammation of the meninges. LIF is a potent pro-inflammatory factor. Cerebrospinal fluid (CSF) contains the growth factors and cytokines whose concentrations have been changed in most neurological diseases. The aim of this study was to determine the LIF conce...
متن کاملAssociation of two polymorphisms in MSH2 and XRCC1 genes with multiple sclerosis in Iranian population
Introduction: To protect genomes of all organisms from internal and external damages and maintain the genome integrity and the continuity of life, repair system has been developed in all living cells. Defects in repair system are responsible for various kinds of disease including cancers and neurodegenerative diseases such as Multiple sclerosis (MS). The relationship between various compone...
متن کاملAberrant expression of leukemia inhibitory factor receptor (LIFR) and leukemia inhibitory factor (LIF) is associated with tubal pregnancy occurrence.
BACKGROUND/AIM Tubal pregnancy is a major cause of maternal death in the first trimester and exploration of its underlying molecular mechanism is of great importance. This study aimed to explore the association of tubal pregnancy with leukemia inhibitory factor (LIF) and leukemia inhibitory factor receptor (LIFR) expression in oviduct tissues. MATERIALS AND METHODS Immunohistochemistry was pe...
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ژورنال
عنوان ژورنال: Journal of Neuroimmunology
سال: 2006
ISSN: 0165-5728
DOI: 10.1016/j.jneuroim.2005.09.016